LILRP2

Across TCGA patient cohorts, LILRP2 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRP2-associated genes across cancer lineages are Notch1, AR, and VHL. Each is linked with LILRP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both LILRP2-to-partner and partner-to-LILRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by LILRP2-low versus LILRP2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRP2→partner) and Y-score (partner→LILRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Notch1 →	+0.222	+2.815	.029	.036	2	3
SKCM	AR →	+0.162	+1.736	.002	.006	3	2
SKCM	VHL →	-0.524	-2.321	.027	.032	3	2
SKCM	Chk1 →	+0.131	+1.204	.048	.041	3	2
UCEC	mTOR_pS2448 →	-0.161	-3.169	.049	.020	3	2
UCEC	NF2 →	+0.292	+3.169	.014	.020	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Notch1 by LILRP2 expression — COAD

Explore this box plot interactively →