LILRB5

Across TCGA patient cohorts, LILRB5 mutation is significantly associated with the RNA expression of many other genes, with 4,646 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRB5-associated genes across cancer lineages are CDC7, MRPL37, and ZWINT. Each is linked with LILRB5 in more than 6 cancer types. Because this analysis shows association rather than direction, both LILRB5-to-partner and partner-to-LILRB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDC7 grouped by LILRB5-low versus LILRB5-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRB5→partner) and Y-score (partner→LILRB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDC7 →	+0.648	+2.807	<.001	.003	3	7
LUAD	MRPL37 →	+0.345	+3.196	<.001	<.001	3	6
LUAD	ZWINT →	+0.802	+2.011	<.001	<.001	3	6
UCEC	SREBF2-AS1 →	+0.388	+1.638	<.001	<.001	3	5
LUAD	SNRPD3 →	+0.330	+2.348	<.001	.003	3	5
UCEC	MCAT →	+0.364	+1.882	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,646 associations by consensus.

CDC7 by LILRB5 expression — LUAD

Explore this box plot interactively →