LILRB5

Across TCGA patient cohorts, LILRB5 mutation is significantly associated with the total protein of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRB5-associated genes across cancer lineages are Cyclin-B1, Rictor_pT1135, and C-Raf. Each is linked with LILRB5 in more than 4 cancer types. Because this analysis shows association rather than direction, both LILRB5-to-partner and partner-to-LILRB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by LILRB5-low versus LILRB5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRB5→partner) and Y-score (partner→LILRB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.767	+2.999	<.001	<.001	3	5
UCEC	Rictor_pT1135 →	-0.072	-1.678	.029	.021	3	4
UCEC	C-Raf →	+0.171	+1.765	<.001	.013	3	4
UCEC	ACC_pS79 →	+0.342	+1.716	.002	.003	3	3
LUSC	NF2 →	+0.165	+1.816	.042	.015	3	3
LUAD	Raptor →	+0.253	+2.824	.002	.034	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

Cyclin-B1 by LILRB5 expression — UCEC

Explore this box plot interactively →