Across TCGA pan-cancer cohorts, LILRB4 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated LILRB4 data layer compared with 30 for mass-spec protein and 7 for mutation status.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LILRB4 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated LILRB4 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.
LUAD, LSCC, and UCEC are the cancer types where LILRB4 mass-spec protein most reproducibly stratifies survival.
mass-spec protein survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.