Across TCGA patient cohorts, LILRB4 mutation is significantly associated with the RNA expression of many other genes, with 3,293 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRB4-associated genes across cancer lineages are TOMM40, SNHG30, and PIMREG. Each is linked with LILRB4 in more than 3 cancer types. Because this analysis shows association rather than direction, both LILRB4-to-partner and partner-to-LILRB4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRB4→partner) and Y-score (partner→LILRB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TOMM40 →	+0.412	+2.815	.003	.001	3	4
SKCM	SNHG30 →	+0.324	+1.367	.009	.004	3	3
UCEC	PIMREG →	+0.807	+2.535	<.001	<.001	3	3
SKCM	NUDT15 →	+0.370	+2.373	.003	.002	3	3
UCEC	ULK3 →	+0.525	+2.736	<.001	<.001	3	3
UCEC	TICRR →	+0.790	+3.807	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,293 associations by consensus.

Exploration

LILRB4 survival (RNA) · tumor vs normal (RNA) · all LILRB4 data types