Across TCGA patient cohorts, LILRB3 mutation is significantly associated with the RNA expression of many other genes, with 3,714 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRB3-associated genes across cancer lineages are ACTR1A, MIR6803, and MTA2. Each is linked with LILRB3 in more than 2 cancer types. Because this analysis shows association rather than direction, both LILRB3-to-partner and partner-to-LILRB3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRB3→partner) and Y-score (partner→LILRB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACTR1A →	+0.355	+2.123	<.001	<.001	3	3
UCEC	MIR6803 →	+0.126	+4.256	<.001	<.001	3	3
UCEC	MTA2 →	+0.402	+2.627	<.001	<.001	3	3
UCEC	GNG3 →	+0.264	+1.841	.008	.001	3	3
SCLC	TAS2R41 →	+0.134	+3.906	<.001	.004	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,714 associations by consensus.

Exploration

LILRB3 survival (RNA) · tumor vs normal (RNA) · all LILRB3 data types