Across TCGA patient cohorts, LILRB3 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRB3-associated genes across cancer lineages are EGFR_pY1068, ERK2, and PDCD4. Each is linked with LILRB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LILRB3-to-partner and partner-to-LILRB3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRB3→partner) and Y-score (partner→LILRB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.197	-1.765	.021	.013	3	2
UCEC	ERK2 →	+0.171	+2.000	.009	.029	3	2
UCEC	PDCD4 →	-0.482	-1.807	.002	.004	3	2
UCEC	S6_pS240_S244 →	+0.282	+3.013	.041	.018	3	2
UCEC	ASNS →	+0.431	+1.807	<.001	.024	3	2
UCEC	cIAP →	+0.093	+1.274	.047	.028	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

LILRB3 survival (RNA) · tumor vs normal (RNA) · all LILRB3 data types