Across TCGA cell cohorts, LILRB3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LILRB3-associated genes across cancer lineages are OR4F4, OR2V1, and NKX2-4. Each is linked with LILRB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LILRB3-to-partner and partner-to-LILRB3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRB3→partner) and Y-score (partner→LILRB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR4F4 →	+0.025	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR2V1 →	+0.042	+4.095	.004	.009	3	1
BREAST	NKX2-4 →	+0.153	+4.672	<.001	.002	3	1
BREAST	UNCX →	+0.240	+4.421	<.001	.004	3	1
BREAST	NCR1 →	+0.195	+4.199	<.001	.007	3	1
BREAST	OR2T5 →	+0.025	+4.781	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

LILRB3 survival (RNA) · tumor vs normal (RNA) · all LILRB3 data types