LILRB2

Across TCGA patient cohorts, LILRB2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,433 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LILRB2-associated genes across cancer lineages are SIRPB1, LILRB1, and JAK3. Each is linked with LILRB2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LILRB2-to-partner and partner-to-LILRB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LILRB2 versus SIRPB1 in UCEC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRB2→partner) and Y-score (partner→LILRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SIRPB1 →	+0.663	+1.145	<.001	.004	3	6
GBM	LILRB1 →	+1.425	+1.528	<.001	<.001	3	6
GBM	JAK3 →	+1.554	+1.581	.001	.001	3	6
GBM	PLEK →	+1.997	+1.686	<.001	<.001	3	6
GBM	SRGN →	+1.597	+1.179	<.001	<.001	3	6
GBM	ADGRE2 →	+0.932	+0.953	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,433 associations by consensus.

LILRB2 vs SIRPB1 — UCEC

Explore this scatter interactively →