LILRB2

Across TCGA cell cohorts, LILRB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,561 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LILRB2-associated GO terms across cancer lineages are Actin nucleation, Interleukin-10-mediated signaling pathway, and Neuroblast differentiation. Each is linked with LILRB2 in more than 3 cancer types. Because this analysis shows association rather than direction, both LILRB2-to-partner and partner-to-LILRB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin nucleation grouped by LILRB2-low versus LILRB2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRB2→partner) and Y-score (partner→LILRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Actin nucleation →	+0.081	+0.007	.004	.009	3	4
BLOOD_Leukemia	Interleukin-10-mediated signaling pathway →	-0.163	-0.928	<.001	<.001	3	3
BLOOD_Leukemia	Neuroblast differentiation →	-0.606	-0.760	<.001	.001	3	3
LARGE_INTESTINE	Negative regulation of cellular response to vascular endothelial growth factor stimulus →	+0.164	+0.006	<.001	.001	3	3
BLOOD_Leukemia	Regulation of calcium ion export across plasma membrane →	+0.074	+1.280	<.001	<.001	3	3
BLOOD_Leukemia	Platelet degranulation →	+0.371	+0.904	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,561 associations by consensus.

Actin nucleation by LILRB2 expression — CNS

Explore this box plot interactively →