LILRB1

Across TCGA patient cohorts, LILRB1 mutation is significantly associated with the RNA expression of many other genes, with 4,354 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRB1-associated genes across cancer lineages are FAM96AP1, TMEM269, and HSBP1L1. Each is linked with LILRB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LILRB1-to-partner and partner-to-LILRB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM96AP1 grouped by LILRB1-low versus LILRB1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRB1→partner) and Y-score (partner→LILRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	FAM96AP1 →	+0.052	+5.592	<.001	<.001	3	3
UCEC	TMEM269 →	+0.219	+2.305	<.001	<.001	3	3
UCEC	HSBP1L1 →	+0.461	+2.595	<.001	<.001	3	3
READ	RN7SL134P →	+0.221	+4.179	<.001	.003	3	3
UCEC	SDK1 →	-0.830	-1.783	<.001	.004	3	3
THCA	CDH18-AS1 →	+0.104	+7.962	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,354 associations by consensus.

FAM96AP1 by LILRB1 expression — LIHC

Explore this box plot interactively →