LILRB1

Across TCGA cell cohorts, LILRB1 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible LILRB1-associated genes across cancer lineages are HELT, SIGLEC7, and OR4C12. Each is linked with LILRB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LILRB1-to-partner and partner-to-LILRB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HELT grouped by LILRB1-low versus LILRB1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRB1→partner) and Y-score (partner→LILRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	HELT →	+0.022	+5.209	<.001	.005	3	1
LUNG_NSCLC_LUAD	SIGLEC7 →	+0.035	+4.215	.006	.002	3	1
LUNG_NSCLC_LUAD	OR4C12 →	+0.013	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	GYPB →	+0.080	+3.544	.001	.009	3	1
OVARY	GZMK →	+0.034	+5.196	<.001	.005	3	1
LARGE_INTESTINE	SH3GL2 →	+1.346	+3.474	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

HELT by LILRB1 expression — BLOOD_Lymphoma

Explore this box plot interactively →