LILRB1

Across TCGA cell cohorts, LILRB1 mutation is significantly associated with the mutation status of many other genes, with 4,654 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LILRB1-associated genes across cancer lineages are KCNH4, PCDHA1, and COL16A1. Each is linked with LILRB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LILRB1-to-partner and partner-to-LILRB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNH4 grouped by LILRB1-low versus LILRB1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRB1→partner) and Y-score (partner→LILRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KCNH4 →	+2.415	+3.510	<.001	<.001	1	5
LUNG_NSCLC_LUSC	PCDHA1 →	+4.228	+4.228	.004	.004	1	4
SKIN	COL16A1 →	+3.548	+3.210	.001	.001	1	4
CNS	COL4A5 →	+4.044	+5.000	.008	.008	1	4
LARGE_INTESTINE	MYH13 →	+2.106	+4.185	<.001	<.001	1	4
LARGE_INTESTINE	SCN4A →	+2.000	+3.169	.002	.002	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,654 associations by consensus.

KCNH4 by LILRB1 expression — LARGE_INTESTINE

Explore this box plot interactively →