LILRA6

Across TCGA patient cohorts, LILRA6 mutation is significantly associated with the RNA expression of many other genes, with 303 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRA6-associated genes across cancer lineages are RNA5SP404, MIR596, and ZNF519P4. Each is linked with LILRA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both LILRA6-to-partner and partner-to-LILRA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP404 grouped by LILRA6-low versus LILRA6-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRA6→partner) and Y-score (partner→LILRA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP404 →	+0.327	+7.731	<.001	.009	3	2
UCEC	MIR596 →	+0.544	+2.546	<.001	.004	3	2
UCEC	ZNF519P4 →	+0.227	+3.129	.002	.002	3	2
UCEC	RNA5SP417 →	+0.483	+2.673	.002	.003	3	2
UCEC	RPL23AP90 →	+0.339	+3.004	.003	<.001	3	2
LUAD	LSP1P3 →	+0.338	+3.311	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 303 associations by consensus.

RNA5SP404 by LILRA6 expression — BRCA

Explore this box plot interactively →