LILRA6

Across TCGA cell cohorts, LILRA6 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LILRA6-associated genes across cancer lineages are TARM1, PCDH11Y, and RSPH6A. Each is linked with LILRA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both LILRA6-to-partner and partner-to-LILRA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TARM1 grouped by LILRA6-low versus LILRA6-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRA6→partner) and Y-score (partner→LILRA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	TARM1 →	+0.020	+4.087	<.001	.009	3	1
URINARY_TRACT	PCDH11Y →	+0.012	+4.087	<.001	.009	3	1
LARGE_INTESTINE	RSPH6A →	+0.110	+3.466	.002	.005	3	1
LARGE_INTESTINE	ENPP6 →	+0.044	+3.378	<.001	.001	3	1
LARGE_INTESTINE	ELOA3DP →	+0.019	+2.688	<.001	.008	3	1
LARGE_INTESTINE	OR13G1 →	+0.016	+3.678	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

TARM1 by LILRA6 expression — URINARY_TRACT

Explore this box plot interactively →