LILRA5

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LILRA5 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRA5-associated genes across cancer lineages are p27_pT157, PCNA, and PKC-b-II_pS660. Each is linked with LILRA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both LILRA5-to-partner and partner-to-LILRA5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRA5→partner) and Y-score (partner→LILRA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCp27_pT157 →+0.128+3.197.003.00933
UCECPCNA →+0.262+2.807.005.00333
UCECPKC-b-II_pS660 →-0.307-2.115.011.01932
UCECPRDX1 →+0.197+2.459.028.01932
UCECAnnexin-1 →+0.664+3.341.003.00532
LUSCMYH11 →-1.477-3.160.001.01922
Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration