LILRA5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LILRA5 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible LILRA5-associated genes across cancer lineages are CCR8, TMEM95, and DUSP29. Each is linked with LILRA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both LILRA5-to-partner and partner-to-LILRA5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRA5→partner) and Y-score (partner→LILRA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUECCR8 →+0.022+5.369<.001.00431
SOFT_TISSUETMEM95 →+0.027+4.930.001.00831
SOFT_TISSUEDUSP29 →+0.087+4.930<.001.00831
BLOOD_LeukemiaGML →+0.088+4.152<.001.00931
BLOOD_LeukemiaMCHR2 →+0.034+4.539<.001.00731
BLOOD_LeukemiaKRTAP12-3 →+0.087+4.539<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration