LILRA4

Across TCGA patient cohorts, LILRA4 mutation is significantly associated with the RNA expression of many other genes, with 2,570 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRA4-associated genes across cancer lineages are LINC01952, ARPC1A, and ADAMTS15. Each is linked with LILRA4 in more than 2 cancer types. Because this analysis shows association rather than direction, both LILRA4-to-partner and partner-to-LILRA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01952 grouped by LILRA4-low versus LILRA4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRA4→partner) and Y-score (partner→LILRA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC01952 →	+0.281	+1.549	<.001	.002	3	3
SKCM	ARPC1A →	+0.328	+1.546	.001	<.001	3	3
SKCM	ADAMTS15 →	-0.540	-2.782	.001	<.001	3	3
SKCM	DLL1 →	-0.413	-1.758	.007	.002	3	3
UCEC	SNX8 →	+0.439	+1.885	.001	.001	3	3
UCEC	MYCL →	-0.625	-1.874	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,570 associations by consensus.

LINC01952 by LILRA4 expression — SKCM

Explore this box plot interactively →