LILRA2

Across TCGA patient cohorts, LILRA2 mutation is significantly associated with the RNA expression of many other genes, with 3,406 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRA2-associated genes across cancer lineages are CIZ1, SMG5, and TRMU. Each is linked with LILRA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both LILRA2-to-partner and partner-to-LILRA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CIZ1 grouped by LILRA2-low versus LILRA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRA2→partner) and Y-score (partner→LILRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CIZ1 →	+0.424	+1.758	.001	.004	3	4
LUAD	SMG5 →	+0.514	+3.193	<.001	<.001	3	4
UCEC	TRMU →	+0.467	+3.031	<.001	<.001	3	3
UCEC	PRMT5 →	+0.682	+3.595	.001	.001	3	3
UCEC	CHD8 →	+0.435	+2.091	.001	.001	3	3
UCEC	SLC7A6OS →	+0.463	+3.831	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,406 associations by consensus.

CIZ1 by LILRA2 expression — UCEC

Explore this box plot interactively →