LILRA2

Across TCGA patient cohorts, LILRA2 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRA2-associated genes across cancer lineages are ATM, STAT3_pY705, and Cyclin-E1. Each is linked with LILRA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both LILRA2-to-partner and partner-to-LILRA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by LILRA2-low versus LILRA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRA2→partner) and Y-score (partner→LILRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.438	-2.115	.010	.017	3	3
UCEC	STAT3_pY705 →	-0.370	-1.990	<.001	.009	3	2
LUAD	Cyclin-E1 →	+0.264	+2.000	.016	.031	3	2
UCEC	eIF4E →	+0.203	+2.169	.010	.003	3	2
UCEC	p62 Lck ligand →	+0.341	+2.321	.005	.033	3	2
UCEC	VHL →	-0.821	-1.415	.001	.046	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

ATM by LILRA2 expression — UCEC

Explore this box plot interactively →