LILRA2

Across TCGA cell cohorts, LILRA2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible LILRA2-associated genes across cancer lineages are CRYGD, OR11H1, and C5orf52. Each is linked with LILRA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LILRA2-to-partner and partner-to-LILRA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYGD grouped by LILRA2-low versus LILRA2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRA2→partner) and Y-score (partner→LILRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CRYGD →	+1.040	+4.817	<.001	.001	3	1
LUNG_SCLC	OR11H1 →	+0.072	+4.044	<.001	.009	3	1
LUNG_SCLC	C5orf52 →	+0.052	+4.643	<.001	.004	3	1
LUNG_SCLC	BTNL2 →	+0.291	+4.044	.001	.009	3	1
LUNG_SCLC	LEUTX →	+0.078	+4.817	<.001	.001	3	1
LUNG_SCLC	PRAMEF4 →	+0.047	+5.169	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

CRYGD by LILRA2 expression — LUNG_SCLC

Explore this box plot interactively →