LIFR

Across TCGA patient cohorts, LIFR RNA expression is significantly associated with the protein abundance of many other proteins, with 17,192 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LIFR-associated proteins across cancer lineages are RPL10A, RPS2, and SORBS1. Each is linked with LIFR in more than 6 cancer types. Because this analysis shows association rather than direction, both LIFR-to-partner and partner-to-LIFR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIFR versus RPL10A in BRCA, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIFR→partner) and Y-score (partner→LIFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL10A →	-0.258	-1.092	<.001	<.001	3	7
CCRCC	RPS2 →	-0.284	-1.001	<.001	<.001	3	7
COAD	SORBS1 →	+0.626	+0.474	<.001	<.001	3	7
HNSC	RPL12 →	-0.209	-0.987	<.001	<.001	3	6
UCEC	TNS1 →	+0.718	+0.962	<.001	<.001	3	6
BRCA	TNS1_S1393 →	+1.112	+1.001	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,192 associations by consensus.

LIFR vs RPL10A — BRCA

Explore this scatter interactively →