LHX6

Across TCGA patient cohorts, LHX6 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,110 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LHX6-associated proteins across cancer lineages are SYNM, VWF, and KANK3. Each is linked with LHX6 in more than 6 cancer types. Because this analysis shows association rather than direction, both LHX6-to-partner and partner-to-LHX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LHX6 versus SYNM in COAD, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LHX6→partner) and Y-score (partner→LHX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SYNM →	+0.896	+0.496	<.001	.001	3	7
UCEC	VWF →	+0.517	+0.489	<.001	<.001	3	7
OV	KANK3 →	+0.538	+0.620	<.001	<.001	3	7
OV	CNRIP1 →	+0.650	+0.461	<.001	<.001	3	6
UCEC	RSU1 →	+0.428	+0.387	.001	.007	2	6
CCRCC	SEC23B →	-0.425	-0.795	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,110 associations by consensus.

LHX6 vs SYNM — COAD

Explore this scatter interactively →