LHX6

Across TCGA cell cohorts, LHX6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,184 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible LHX6-associated GO terms across cancer lineages are Cerebral cortex GABAergic interneuron migration, Cerebral cortex GABAergic interneuron development, and Interneuron migration. Each is linked with LHX6 in more than 16 cancer types. Because this analysis shows association rather than direction, both LHX6-to-partner and partner-to-LHX6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cerebral cortex GABAergic interneuron migration grouped by LHX6-low versus LHX6-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LHX6→partner) and Y-score (partner→LHX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cerebral cortex GABAergic interneuron migration →	+1.304	+2.384	.003	.001	3	17
LUNG_NSCLC_LUSC	Cerebral cortex GABAergic interneuron development →	+1.304	+2.384	.003	.001	3	17
LUNG_NSCLC_LUSC	Interneuron migration →	+1.367	+2.219	.004	.002	3	15
LUNG_NSCLC_LUAD	Cerebral cortex GABAergic interneuron differentiation →	+1.044	+2.142	<.001	<.001	3	12
OESOPHAGUS	Establishment of mitotic spindle localization →	+0.117	+2.514	<.001	<.001	3	10
SKIN	Transcription initiation at RNA polymerase III promoter →	+0.073	+0.947	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,184 associations by consensus.

Cerebral cortex GABAergic interneuron migration by LHX6 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →