LHX4

Across TCGA patient cohorts, LHX4 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,509 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LHX4-associated proteins across cancer lineages are DHX9, GATAD2B, and TSN. Each is linked with LHX4 in more than 6 cancer types. Because this analysis shows association rather than direction, both LHX4-to-partner and partner-to-LHX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LHX4 versus DHX9 in LSCC, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LHX4→partner) and Y-score (partner→LHX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DHX9 →	+0.283	+0.659	<.001	<.001	3	7
GBM	GATAD2B →	+0.313	+0.614	<.001	<.001	3	7
LUAD	TSN →	+0.287	+0.568	<.001	<.001	2	7
HNSC	PARP1 →	+0.427	+0.468	<.001	<.001	3	6
GBM	PRCC →	+0.293	+0.696	<.001	<.001	3	6
HNSC	RO60 →	+0.266	+0.622	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,509 associations by consensus.

LHX4 vs DHX9 — LSCC

Explore this scatter interactively →