LHPP

Across TCGA patient cohorts, LHPP RNA expression is significantly associated with the protein abundance of many other proteins, with 13,414 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LHPP-associated proteins across cancer lineages are NT5C2, OAT, and PDZD8_S538. Each is linked with LHPP in more than 4 cancer types. Because this analysis shows association rather than direction, both LHPP-to-partner and partner-to-LHPP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LHPP versus NT5C2 in OV, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LHPP→partner) and Y-score (partner→LHPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NT5C2 →	+0.432	+0.651	.002	<.001	3	5
LSCC	OAT →	+0.682	+0.546	<.001	<.001	3	5
PDAC	PDZD8_S538 →	+0.473	+0.262	<.001	.003	3	4
GBM	DUSP12 →	-0.316	-0.957	<.001	<.001	3	4
CCRCC	FAM160B1 →	+0.217	+0.449	<.001	<.001	3	4
CCRCC	NEFL_S472 →	+1.258	+0.425	.006	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,414 associations by consensus.

LHPP vs NT5C2 — OV

Explore this scatter interactively →