LHPP

Across TCGA cell cohorts, LHPP protein abundance is significantly associated with the RNA expression of many other genes, with 4,190 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LHPP-associated genes across cancer lineages are ORMDL2, ANKRD28, and SCAF4. Each is linked with LHPP in more than 5 cancer types. Because this analysis shows association rather than direction, both LHPP-to-partner and partner-to-LHPP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LHPP versus ORMDL2 in OVARY, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHPP→partner) and Y-score (partner→LHPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ORMDL2 →	+0.646	+0.595	.001	.003	3	6
BREAST	ANKRD28 →	-0.786	-0.509	.002	.005	3	6
PANCREAS	SCAF4 →	-0.457	-0.828	.005	.003	3	6
URINARY_TRACT	ACD →	-0.817	-0.534	.005	.005	3	5
URINARY_TRACT	LAMA3 →	+3.432	+0.519	.007	<.001	3	5
BLOOD_Myeloma	MFSD5 →	+1.242	+1.069	.009	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,190 associations by consensus.

LHPP vs ORMDL2 — OVARY

Explore this scatter interactively →