Across TCGA patient cohorts, LHFPL5 mutation is significantly associated with the RNA expression of many other genes, with 1,099 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LHFPL5-associated genes across cancer lineages are RPL7P31, LINC02348, and RNA5SP19. Each is linked with LHFPL5 in more than 2 cancer types. Because this analysis shows association rather than direction, both LHFPL5-to-partner and partner-to-LHFPL5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL5→partner) and Y-score (partner→LHFPL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL7P31 →	+0.165	+2.946	.003	.003	3	3
UCEC	LINC02348 →	+0.620	+2.719	<.001	<.001	3	3
READ	RNA5SP19 →	+1.489	+5.039	<.001	.008	3	3
BLCA	MATR3P1 →	+0.141	+4.314	<.001	.009	3	3
UCEC	RNU2-58P →	+0.460	+2.398	<.001	.001	3	3
UCEC	DBF4B →	+0.453	+3.365	.007	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,099 associations by consensus.

Exploration

LHFPL5 survival (RNA) · tumor vs normal (RNA) · all LHFPL5 data types