LHFPL4

Across TCGA patient cohorts, LHFPL4 protein abundance is significantly associated with the RNA expression of many other genes, with 387 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LHFPL4-associated genes across cancer lineages are CPNE6, DNAJC5, and SNPH. Each is linked with LHFPL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LHFPL4-to-partner and partner-to-LHFPL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LHFPL4 versus CPNE6 in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL4→partner) and Y-score (partner→LHFPL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CPNE6 →	+0.880	+0.409	<.001	.005	3	1
GBM	DNAJC5 →	+0.196	+0.383	.008	.009	3	1
GBM	SNPH →	+0.858	+0.570	.001	.007	3	1
GBM	KIF3B →	+0.368	+0.609	.005	.009	3	1
GBM	AP3B2 →	+0.634	+0.461	<.001	.001	3	1
GBM	FCER2 →	+0.476	+0.394	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 387 associations by consensus.

LHFPL4 vs CPNE6 — GBM

Explore this scatter interactively →