LHFPL4

Across TCGA patient cohorts, LHFPL4 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,660 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LHFPL4-associated proteins across cancer lineages are RELL2, RIMS1_S713, and RIMS1_S723. Each is linked with LHFPL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LHFPL4-to-partner and partner-to-LHFPL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LHFPL4 versus RELL2 in GBM, with a Pearson correlation of 0.47.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL4→partner) and Y-score (partner→LHFPL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RELL2 →	+0.899	+0.548	<.001	.001	3	1
GBM	RIMS1_S713 →	+1.429	+0.606	<.001	<.001	3	1
GBM	RIMS1_S723 →	+1.649	+0.573	.005	.006	3	1
GBM	RIMS4_S257 →	+0.745	+0.699	<.001	<.001	3	1
GBM	RUNDC3A_T215 →	+0.357	+0.600	.002	<.001	3	1
GBM	SCN2A_S526 →	+1.685	+0.699	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,660 associations by consensus.

LHFPL4 vs RELL2 — GBM

Explore this scatter interactively →