LHFPL4

Across TCGA cell cohorts, LHFPL4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible LHFPL4-associated genes across cancer lineages are ASB17 and OR4C12. Each is linked with LHFPL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LHFPL4-to-partner and partner-to-LHFPL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by LHFPL4-low versus LHFPL4-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL4→partner) and Y-score (partner→LHFPL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR4C12 →	+0.019	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ASB17 by LHFPL4 expression — OVARY

Explore this box plot interactively →