Across TCGA patient cohorts, LHFPL3 protein abundance is significantly associated with the RNA expression of many other genes, with 685 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LHFPL3-associated genes across cancer lineages are POLR2F, SEPTIN3, and TRPC4AP. Each is linked with LHFPL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LHFPL3-to-partner and partner-to-LHFPL3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL3→partner) and Y-score (partner→LHFPL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	POLR2F →	+0.570	+0.522	<.001	<.001	3	1
GBM	SEPTIN3 →	+0.847	+0.350	.007	.007	3	1
GBM	TRPC4AP →	-0.152	-0.283	.004	.004	3	1
GBM	PROCR →	-0.423	-0.261	.003	.008	3	1
GBM	COL20A1 →	+1.859	+0.421	<.001	<.001	3	1
GBM	HM13 →	-0.325	-0.464	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 685 associations by consensus.

Exploration

LHFPL3 survival (RNA) · tumor vs normal (RNA) · all LHFPL3 data types