Across TCGA patient cohorts, LHFPL3 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LHFPL3-associated genes across cancer lineages are eIF4E, mTOR_pS2448, and ATM. Each is linked with LHFPL3 in more than 2 cancer types. Because this analysis shows association rather than direction, both LHFPL3-to-partner and partner-to-LHFPL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL3→partner) and Y-score (partner→LHFPL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.139	+1.392	.045	.019	3	3
UCEC	mTOR_pS2448 →	-0.130	-2.571	.008	.010	3	3
UCEC	ATM →	-0.461	-3.794	.002	<.001	3	3
UCEC	FASN →	+0.291	+1.392	.025	.019	3	2
UCEC	Rad50 →	-0.204	-1.652	.010	.006	3	2
UCEC	Caspase-7-cleavedD198 →	+0.680	+2.522	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

LHFPL3 survival (RNA) · tumor vs normal (RNA) · all LHFPL3 data types