LHFPL3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LHFPL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,055 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible LHFPL3-associated GO terms across cancer lineages are Negative regulation of macrophage cytokine production, Skeletal myofibril assembly, and Natural killer cell chemotaxis. Each is linked with LHFPL3 in more than 3 cancer types. Because this analysis shows association rather than direction, both LHFPL3-to-partner and partner-to-LHFPL3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL3→partner) and Y-score (partner→LHFPL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaNegative regulation of macrophage cytokine production →-0.240-0.046.002.00334
LUNG_SCLCSkeletal myofibril assembly →-0.673-1.001<.001<.00134
SOFT_TISSUENatural killer cell chemotaxis →-0.704-0.219.002.00633
LUNG_SCLCNegative regulation of immune effector process →-0.175-1.242<.001.00433
SKINNegative regulation of cell-matrix adhesion →-0.095-0.358<.001.00233
LARGE_INTESTINEDentinogenesis →-0.584-0.311.009.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,055 associations by consensus.

Exploration