LHFPL3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LHFPL3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LHFPL3-associated genes across cancer lineages are S100A7A and OR52K1. Each is linked with LHFPL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LHFPL3-to-partner and partner-to-LHFPL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL3→partner) and Y-score (partner→LHFPL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaS100A7A →+0.026+4.643<.001.00531
BLOOD_LymphomaOR52K1 →+0.011+5.169<.001.00131
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration