LHFPL2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LHFPL2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,082 significant associations in total. OV shows the largest number of these associations.

The most reproducible LHFPL2-associated genes across cancer lineages are FCGR3A, ELFN1, and ELMO1. Each is linked with LHFPL2 in more than 3 cancer types. Because this analysis shows association rather than direction, both LHFPL2-to-partner and partner-to-LHFPL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LHFPL2 versus FCGR3A in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL2→partner) and Y-score (partner→LHFPL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCFCGR3A →+1.583+0.793<.001<.00124
COADELFN1 →+0.719+0.405.009.00733
OVELMO1 →+1.117+0.475<.001<.00133
HNSCCD86 →+1.102+0.744<.001.00124
OVLY96 →+1.047+0.400.001.00333
HNSCCCR1 →+1.245+0.717<.001.00724
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,082 associations by consensus.

LHFPL2 vs FCGR3A — HNSC

Per-sample scatter of LHFPL2 vs FCGR3A in HNSC (Pearson r = 0.28).

Explore this scatter interactively →

Exploration