LHFPL2

Across TCGA cell cohorts, LHFPL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,644 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LHFPL2-associated GO terms across cancer lineages are Positive regulation of fertilization, Regulation of cell-substrate junction organization, and Regulation of cell-matrix adhesion. Each is linked with LHFPL2 in more than 18 cancer types. Because this analysis shows association rather than direction, both LHFPL2-to-partner and partner-to-LHFPL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of fertilization grouped by LHFPL2-low versus LHFPL2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL2→partner) and Y-score (partner→LHFPL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of fertilization →	+1.759	+3.275	<.001	<.001	3	19
BONE	Regulation of cell-substrate junction organization →	+0.165	+1.888	<.001	<.001	3	13
BONE	Regulation of cell-matrix adhesion →	+0.163	+2.017	<.001	<.001	3	12
BONE	Regulation of protein maturation →	+0.192	+1.820	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.230	+1.477	.007	.003	3	11
BONE	Negative regulation of small GTPase mediated signal transduction →	+0.091	+1.491	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,644 associations by consensus.

Positive regulation of fertilization by LHFPL2 expression — BLOOD_Lymphoma

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