LHFPL1

Across TCGA patient cohorts, LHFPL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,689 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LHFPL1-associated proteins across cancer lineages are PLCB4, MT3, and AMOT. Each is linked with LHFPL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both LHFPL1-to-partner and partner-to-LHFPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LHFPL1 versus PLCB4 in HNSC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL1→partner) and Y-score (partner→LHFPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PLCB4 →	+0.734	+1.141	<.001	<.001	3	4
UCEC	MT3 →	+1.637	+0.570	<.001	.001	3	4
GBM	AMOT →	+0.562	+1.060	<.001	<.001	3	4
GBM	WFS1 →	+0.545	+0.942	<.001	<.001	3	3
HNSC	MTARC2 →	+0.671	+0.852	<.001	<.001	3	3
UCEC	APOO →	+0.409	+0.450	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,689 associations by consensus.

LHFPL1 vs PLCB4 — HNSC

Explore this scatter interactively →