LHFPL1

Across TCGA cell cohorts, LHFPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,861 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LHFPL1-associated GO terms across cancer lineages are Proton transmembrane transport, Aerobic respiration, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with LHFPL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LHFPL1-to-partner and partner-to-LHFPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton transmembrane transport grouped by LHFPL1-low versus LHFPL1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL1→partner) and Y-score (partner→LHFPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Proton transmembrane transport →	+0.071	+0.138	<.001	<.001	3	8
OVARY	Aerobic respiration →	+0.073	+0.172	.001	.005	3	8
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.085	+0.778	<.001	<.001	3	7
STOMACH	Negative regulation of transcription by RNA polymerase I →	+0.089	+0.122	.005	.003	3	6
OVARY	Regulation of transcription elongation by RNA polymerase II →	+0.048	+0.158	.001	.004	3	6
OVARY	Cellular respiration →	+0.060	+0.104	<.001	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,861 associations by consensus.

Proton transmembrane transport by LHFPL1 expression — OVARY

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