LHFPL1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LHFPL1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LHFPL1-associated genes across cancer lineages are OR5V1. Each is linked with LHFPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LHFPL1-to-partner and partner-to-LHFPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5V1 grouped by LHFPL1-low versus LHFPL1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL1→partner) and Y-score (partner→LHFPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR5V1 →+0.008+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR5V1 by LHFPL1 expression — LARGE_INTESTINE

Box plot of OR5V1 in LHFPL1-low vs LHFPL1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration