LGSN

Across TCGA patient cohorts, LGSN RNA expression is significantly associated with the go_rna of many other GO terms, with 6,876 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LGSN-associated GO terms across cancer lineages are Intracellular protein transmembrane transport, mRNA 3'-end processing, and Response to starvation. Each is linked with LGSN in more than 15 cancer types. Because this analysis shows association rather than direction, both LGSN-to-partner and partner-to-LGSN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular protein transmembrane transport grouped by LGSN-low versus LGSN-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGSN→partner) and Y-score (partner→LGSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Intracellular protein transmembrane transport →	+0.058	+0.577	<.001	<.001	3	15
STAD	mRNA 3'-end processing →	+0.065	+0.453	<.001	<.001	3	15
KIRP	Response to starvation →	+0.021	+0.159	<.001	<.001	3	15
STAD	Protein modification by small protein removal →	+0.062	+0.396	<.001	.005	1	16
STAD	Regulation of protein ubiquitination →	+0.048	+0.400	<.001	<.001	3	14
STAD	Regulation of DNA-templated transcription elongation →	+0.054	+0.454	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,876 associations by consensus.

Intracellular protein transmembrane transport by LGSN expression — STAD

Explore this box plot interactively →