LGSN

Across TCGA patient cohorts, LGSN protein abundance is significantly associated with the protein abundance of many other proteins, with 14,761 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LGSN-associated proteins across cancer lineages are GBE1, PGM1_S117, and SMNDC1. Each is linked with LGSN in more than 6 cancer types. Because this analysis shows association rather than direction, both LGSN-to-partner and partner-to-LGSN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGSN versus GBE1 in CCRCC, with a Pearson correlation of 0.87.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LGSN→partner) and Y-score (partner→LGSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GBE1 →	+0.749	+1.059	<.001	<.001	3	7
CCRCC	PGM1_S117 →	+0.569	+1.068	<.001	.001	3	5
LSCC	SMNDC1 →	-0.295	-0.808	<.001	<.001	3	4
LUAD	TUT7_T1414 →	-1.915	-0.784	<.001	<.001	3	4
LUAD	ZC3H14_S620 →	-1.011	-0.600	<.001	<.001	3	4
UCEC	PRICKLE2_S806 →	+0.994	+0.848	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,761 associations by consensus.

LGSN vs GBE1 — CCRCC

Explore this scatter interactively →