LGSN

Across TCGA cell cohorts, LGSN RNA expression is significantly associated with the go_rna of many other GO terms, with 1,004 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LGSN-associated GO terms across cancer lineages are Regulation of TORC1 signaling, Protein targeting to lysosome, and tRNA aminoacylation for protein translation. Each is linked with LGSN in more than 4 cancer types. Because this analysis shows association rather than direction, both LGSN-to-partner and partner-to-LGSN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of TORC1 signaling grouped by LGSN-low versus LGSN-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGSN→partner) and Y-score (partner→LGSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of TORC1 signaling →	+0.041	+0.692	.004	.007	3	5
LIVER	Protein targeting to lysosome →	+0.053	+1.509	.003	.005	3	5
CNS	tRNA aminoacylation for protein translation →	+0.051	+0.075	<.001	.004	3	5
CNS	Regulation of actin nucleation →	+0.054	+0.128	<.001	<.001	3	4
OVARY	Positive regulation of TORC1 signaling →	+0.051	+0.679	.006	.005	3	4
OVARY	Copper ion export →	-0.146	-0.866	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,004 associations by consensus.

Regulation of TORC1 signaling by LGSN expression — OVARY

Explore this box plot interactively →