Across TCGA cell cohorts, LGR4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,509 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LGR4-associated GO terms across cancer lineages are Metanephric glomerulus development, Metanephric tubule morphogenesis, and Metanephric nephron tubule morphogenesis. Each is linked with LGR4 in more than 14 cancer types. Because this analysis shows association rather than direction, both LGR4-to-partner and partner-to-LGR4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGR4→partner) and Y-score (partner→LGR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Metanephric glomerulus development →	+1.527	+1.176	<.001	.007	3	15
BREAST	Metanephric tubule morphogenesis →	+0.231	+1.565	<.001	<.001	3	12
BREAST	Metanephric nephron tubule morphogenesis →	+0.231	+1.565	<.001	<.001	3	12
OVARY	Metanephric epithelium development →	+0.222	+1.613	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Bone mineralization →	+0.130	+1.199	<.001	<.001	3	10
OVARY	Metanephric nephron epithelium development →	+0.230	+1.424	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,509 associations by consensus.

Exploration

LGR4 survival (RNA) · tumor vs normal (RNA) · all LGR4 data types