LGALS9C

Across TCGA patient cohorts, LGALS9C RNA expression is significantly associated with the go_rna of many other GO terms, with 6,965 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible LGALS9C-associated GO terms across cancer lineages are Positive regulation of tumor necrosis factor superfamily cytokine production, Positive regulation by symbiont of entry into host, and Response to protozoan. Each is linked with LGALS9C in more than 17 cancer types. Because this analysis shows association rather than direction, both LGALS9C-to-partner and partner-to-LGALS9C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of tumor necrosis factor superfamily cytokine production grouped by LGALS9C-low versus LGALS9C-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS9C→partner) and Y-score (partner→LGALS9C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Positive regulation of tumor necrosis factor superfamily cytokine production →	+0.044	+0.128	<.001	<.001	3	18
TGCT	Positive regulation by symbiont of entry into host →	+0.069	+0.210	<.001	.001	2	18
TGCT	Response to protozoan →	+0.109	+0.161	<.001	<.001	2	17
SKCM	Antigen processing and presentation of exogenous peptide antigen via MHC class II →	+0.092	+0.093	<.001	<.001	3	16
SKCM	Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II →	+0.078	+0.099	<.001	<.001	3	16
DLBC	Positive regulation of superoxide anion generation →	+0.089	+0.510	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,965 associations by consensus.

Positive regulation of tumor necrosis factor superfamily cytokine production by LGALS9C expression — UCS

Explore this box plot interactively →