LGALS9C

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LGALS9C mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LGALS9C-associated genes across cancer lineages are Ku80 and HER3_pY1289. Each is linked with LGALS9C in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS9C-to-partner and partner-to-LGALS9C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by LGALS9C-low versus LGALS9C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS9C→partner) and Y-score (partner→LGALS9C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECKu80 →+0.330+2.820.022.03621
UCECHER3_pY1289 →+0.110+2.833.038.03511
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Ku80 by LGALS9C expression — UCEC

Box plot of Ku80 in LGALS9C-low vs LGALS9C-high samples in UCEC.

Explore this box plot interactively →

Exploration