LGALS9C

Across TCGA cell cohorts, LGALS9C RNA expression is significantly associated with the go_rna of many other GO terms, with 1,716 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LGALS9C-associated GO terms across cancer lineages are Negative regulation of mast cell degranulation, Negative regulation of myeloid leukocyte mediated immunity, and Positive regulation of iron ion transport. Each is linked with LGALS9C in more than 10 cancer types. Because this analysis shows association rather than direction, both LGALS9C-to-partner and partner-to-LGALS9C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mast cell degranulation grouped by LGALS9C-low versus LGALS9C-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS9C→partner) and Y-score (partner→LGALS9C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of mast cell degranulation →	+1.681	+0.911	<.001	.001	2	11
STOMACH	Negative regulation of myeloid leukocyte mediated immunity →	+2.017	+0.899	<.001	.002	2	9
PANCREAS	Positive regulation of iron ion transport →	+1.358	+1.463	<.001	<.001	3	8
PANCREAS	Positive regulation of iron ion transmembrane transport →	+1.358	+1.463	<.001	<.001	3	8
STOMACH	Cell-cell adhesion mediated by cadherin →	+0.155	+0.603	.002	.004	2	8
BREAST	Regulation of lymphocyte apoptotic process →	+0.087	+0.824	.001	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,716 associations by consensus.

Negative regulation of mast cell degranulation by LGALS9C expression — STOMACH

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