LGALS9C

Across TCGA cell cohorts, LGALS9C mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LGALS9C-associated genes across cancer lineages are C20orf85, OR1L4, and TMEM174. Each is linked with LGALS9C in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS9C-to-partner and partner-to-LGALS9C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C20orf85 grouped by LGALS9C-low versus LGALS9C-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS9C→partner) and Y-score (partner→LGALS9C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C20orf85 →	+0.115	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR1L4 →	+0.072	+5.369	<.001	.004	3	1
SOFT_TISSUE	TMEM174 →	+0.029	+4.930	<.001	.008	3	1
SOFT_TISSUE	OR4D6 →	+0.046	+5.977	<.001	.001	3	1
SOFT_TISSUE	OR51G2 →	+0.036	+5.369	<.001	.004	3	1
SOFT_TISSUE	GFRAL →	+0.016	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

C20orf85 by LGALS9C expression — SOFT_TISSUE

Explore this box plot interactively →