LGALS9

Across TCGA patient cohorts, LGALS9 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,147 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LGALS9-associated proteins across cancer lineages are PSMB5, OAS2, and PARP14. Each is linked with LGALS9 in more than 8 cancer types. Because this analysis shows association rather than direction, both LGALS9-to-partner and partner-to-LGALS9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS9 versus PSMB5 in LSCC, with a Pearson correlation of -0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS9→partner) and Y-score (partner→LGALS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PSMB5 →	-0.578	-0.897	<.001	<.001	3	9
LSCC	OAS2 →	+1.035	+0.922	<.001	<.001	3	9
OV	PARP14 →	+0.462	+0.822	<.001	.007	3	9
HNSC	RNF213 →	+0.370	+0.801	<.001	<.001	3	8
HNSC	CD74 →	+0.605	+0.655	<.001	<.001	3	8
LSCC	CMPK2 →	+0.678	+0.850	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,147 associations by consensus.

LGALS9 vs PSMB5 — LSCC

Explore this scatter interactively →