LGALS9

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LGALS9 protein abundance is significantly associated with the RNA expression of many other genes, with 14,419 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LGALS9-associated genes across cancer lineages are UBE2L6, ETV7, and SLC15A3. Each is linked with LGALS9 in more than 9 cancer types. Because this analysis shows association rather than direction, both LGALS9-to-partner and partner-to-LGALS9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS9 versus UBE2L6 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS9→partner) and Y-score (partner→LGALS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCUBE2L6 →+1.055+0.608<.001<.001310
BRCAETV7 →+1.671+0.576<.001<.00139
HNSCSLC15A3 →+0.963+0.764<.001<.00139
OVOAS2 →+1.510+0.689.001<.00139
HNSCTRIM22 →+1.180+0.583<.001<.00139
HNSCIL15RA →+0.709+0.619<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,419 associations by consensus.

LGALS9 vs UBE2L6 — HNSC

Per-sample scatter of LGALS9 vs UBE2L6 in HNSC (Pearson r = 0.28).

Explore this scatter interactively →

Exploration